A ph of 4 at body temperature of 37 c causes depurination of dna leaving apurinic ap sites in dna especially loss of guanine.
Dna stress mat meaning.
Over time they tend to get shorter.
If you are under enough stress.
We ll dive into the recent research surrounding telomere shortening cancer and aging.
Dna replication stress refers to the state of a cell whose genome is exposed to various stresses.
Oxidative stress is an imbalance between free radicals and antioxidants in your body.
Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell including.
Although the authors could not explain how this modification occurs nicholas warren a ph d.
Certain sections of your genetic code allowing other genes to be expressed in your body.
Dietary carbohydrates can cause a dramatic decrease in ph in oral biofilms to values of 4 and below acid stress.
Epigenetics meaning attached to the dna is the study of such modifications.
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system s ability to readily detoxify the reactive intermediates or to repair the resulting damage.
Oxidative stress can damage cells proteins and dna which can contribute to aging.
This post was written with alan cudmore.
Telomeres are small structures that protect the ends of your chromosomes.
It may also play a role in development of a range of health conditions including diabetes cancer and.
The events that contribute to replication stress occur during dna replication and can result in a stalled replication fork.
The uneven number allows.
There are many events that contribute to replication stress including.
The dutch famine of 1944 was a terrible time for many in the netherlands with around 4 5m people affected and reliant on soup kitchens after food supplies were stopped from getting into the.
Biofilm on the surface of teeth is frequently subject to oxidative stress and acid stress.
Free radicals are oxygen containing molecules with an uneven number of electrons.